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Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:5mg DOTA bifucational chelator containing an

SKU 92248367065
4.1
EUR445.00 EUR479.00

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Description

DOTA bifucational chelator containing an alcohol group

306 SMILES BrCCCCCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Azidobenzoyl-CA CAS Number Related CAS Molecular Formula C17H25ClN4O3 Molecular Weight 368

009 Purity (HPLC) >= 95% Solubility DMSO

46 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC(=CC=C2C([O-])=O)C(O)=O)=[N+](C)C)=C1 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:5mg DOTA bifucational chelator containing anSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a

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