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OC(=O)C1=CC=C2C(=O)OC3(C2=C1)C1=CC=C(O)C=C1OC1=C3C=CC(O)=C1 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only
Product Name Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C56H94N8O21 Molecular Weight 1215
S)-AHPC-CO-C5-NH2 HCl Synonyms CAS Number 2415256-20-9 Related CAS 2170695-19-7 (free base) Molecular Formula C28H43Cl2N5O4S Molecular Weight 616
Product Name Methyl 5-bromo-2-[(methyl-d3)amino]benzoate Synonyms CAS Number n/a Related CAS Molecular Formula C9H10BrNO2 Molecular Weight 247
Product Name Lenalidomide-CO-PEG4-C2-Cl Synonyms Lenalidomide-4'-CO-PEG4-C2-Cl CAS Number n/a Related CAS Molecular Formula C24H32ClN3O8 Molecular Weight 525
Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-Exatecan AHPC OC(=O)C1=CC=C2C(=O)OC3(C2=C1)C1=CC=C(O)C=C1OC1=C3C=CC(O)=C1 Purity (HPLC): ≥ 95%SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I
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