DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:1mg Product Name BC-TCO Synonyms CLIP-TCO

Product Name BC-TCO Synonyms CLIP-TCO CAS Number Related CAS Molecular Formula C21H26N4O3 Molecular Weight 382

764 Purity (HPLC) >= 95% Physical Appearance Dark blue solid Optical Properties Abs/Em Maxima: 649/672 nm Solubility DMSO Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DOTA-tris(t-Bu)ester-C2-DBCO Synonyms CAS Number n/a Related CAS Molecular Formula C46H66N6O8 Molecular Weight 831

Product Name Lenalidomide-CO-C3-amine HCl Synonyms Lenalidomide-4'-CO-C3-amine HCl CAS Number 2353563-41-2 Related CAS Molecular Formula C17H21ClN4O4 Molecular Weight 380

512 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:1mg Product Name BC-TCO Synonyms CLIP-TCOSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further