Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB Size:100mg Product Name Thalidomide-5'-alkyne-C3-OH Synonyms CAS

Product Name Thalidomide-5'-alkyne-C3-OH Synonyms CAS Number 2357113-47-2  Related CAS Molecular Formula C18H16N2O5 Molecular Weight 340

78 SMILES Cl

and biochemical research

Contains an E3 ligase ligand with alkyl linker and a terminal piperazine moiety

827 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB Size:100mg Product Name Thalidomide-5'-alkyne-C3-OH Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine