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Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:25mg Product Name MaP555 Acid Synonyms

SKU 8086469358
4.7
USD495.00 USD515.00

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Description

Product Name MaP555 Acid Synonyms CAS Number 2434651-26-8 Related CAS Molecular Formula C27H28N4O6S Molecular Weight 536

Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein

S)-AHPC-CO-PEG4-C2-Br Synonyms CAS Number n/a Related CAS Molecular Formula C33H49BrN4O8S Molecular Weight 741

96 SMILES ClCCOCCOCCOCCOCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

… Chekler

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:25mg Product Name MaP555 Acid SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to

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