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MC-Val-Cit-PAB(m-PEG8)-Exatecan tamra Product Name Pomalidomide-5'-C6-OH Synonyms CAS

SKU 80518422936
4.4
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Description

Product Name Pomalidomide-5'-C6-OH Synonyms CAS Number 2493430-98-9 Related CAS Molecular Formula C19H23N3O5 Molecular Weight 373

Product Name Pomalidomide-CO-C5-azide Synonyms Pomalidomide-4'-CO-C5-azide CAS Number 2227423-33-6 Related CAS Molecular Formula C19H20N6O5 Molecular Weight 412

097 SMILES [2H]C([2H])([2H])NCC1=CC=C(Br)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-O-acetamido-C3-azide Synonyms Thalidomide-4'-O-acetamido-C3-azide CAS Number n/a Related CAS Molecular Formula C18H18N6O6 Molecular Weight 414

Product Name Thalidomide-O-acetamido-C2-amine HCl Synonyms Thalidomide-4'-O-acetamido-C2-amine HCl CAS Number 2341841-02-7 Related CAS Molecular Formula C17H19ClN4O6 Molecular Weight 410

MC-Val-Cit-PAB(m-PEG8)-Exatecan tamra Product Name Pomalidomide-5'-C6-OH Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,

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