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Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE bc S)-AHPC-CO-C10-NH2 HCl Synonyms CAS Number

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Description

S)-AHPC-CO-C10-NH2 HCl Synonyms CAS Number 2341796-75-4 Related CAS 2341796-74-3 (free base) Molecular Formula C33H53Cl2N5O4S Molecular Weight 686

Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders

Mixed isomer of 5 and 6-FAM ethylenediamine

Product Name Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C94H155N13O29 Molecular Weight 1931

Product Name CRBN5-CLIP-0C-PIP Synonyms CAS Number N/A Related CAS N/A Molecular Formula C31H31N7O6 Molecular Weight 597

Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE bc S)-AHPC-CO-C10-NH2 HCl Synonyms CAS NumberSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous

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