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The PNP (para-nitrophenyl) moiety serves as an activating leaving group
41 SMILES BrCCOCCOCCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
e202410025
Product Name Fmoc-Val-Cit-PAB-PNP Synonyms Fmoc-VC-PAB-PNP CAS Number 863971-53-3 Related CAS Molecular Formula C40H42N6O10 Molecular Weight 766
SIRT5) that remove this modification
Val-Cit-PAB mal-lys-m-peg4 The PNP (para-nitrophenyl) moiety servesVal Cit PAB is a cleavable ADC linker featuring a ValCit dipeptide and a para aminobenzyl (PAB) spacer. The ValCit sequence is selectively cleaved by cathepsin B in lysosomes, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug. Product Name Val Cit PAB Synonyms VC PAB OH CAS Number 159857 79 1 Related CAS Molecular Formula C18H29N5O4 Molecular Weight 379. 461 Purity (HPLC) >= 95% Solubility DMSO, DMF Shipping
