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Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Lenalidomide Product Name DOTA-PEG4 Synonyms CAS

SKU 74755470282
4.1
EUR495.00 EUR517.00

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Description

Product Name DOTA-PEG4 Synonyms CAS Number n/a Related CAS Molecular Formula C24H45N5O11 Molecular Weight 579

Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C96H155N15O28 Molecular Weight 1967

84 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCO)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

73 Purity (HPLC) >= 95% Physical Appearance Red Solid Optical Properties Abs/Em Maxima: 558/578 nm Solubility DMSO

NCCOCCOCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Lenalidomide Product Name DOTA-PEG4 Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload

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