Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg Product Name 5(6)-ROX PEG3 azide

Product Name 5(6)-ROX PEG3 azide Synonyms 5-(and 6)-Carboxy-X-rhodamine PEG3 Azide CAS Number N/A Related CAS Molecular Formula C41H46N6O7 Molecular Weight 734

Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C56H90N10O20 Molecular Weight 1223

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Phthalimidinoglutarimide-propargyl-PEG2-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG2-OH CAS Number n/a Related CAS Molecular Formula C20H22N2O6 Molecular Weight 386

182 SMILES [2H]C([2H])([2H])OC1=CC=C(C)C(=C1)N(=O)=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg Product Name 5(6)-ROX PEG3 azideSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate