Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) Size:10mg It reduces mHTT levels through

It reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule-associated protein 1A/1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT)

SNAP-tag is a self-labeling protein derived from human O6-alkylguanine-DNA-alkyltransferase

93 SMILES Cl

Product Name CA-N3 Synonyms Azidoacyl-Halo

Product Name Mal-Lys(m-PEG4)-Val-Cit-PAB Synonyms CAS Number Related CAS Molecular Formula C38H59N7O12 Molecular Weight 805

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) Size:10mg It reduces mHTT levels throughSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from