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DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE deuterium-labeled-aldehyde 664 SMILES NCCOCCOCCOCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC)

SKU 65837949592
4.4
USD445.00 USD475.00

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Description

664 SMILES NCCOCCOCCOCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Tetramethylrhodamine-6 C2 maleimide is a good alternative to tetramethylrhodamine-6-maleimide andis a single isomer

297 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(NCC#C)=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

821 Purity (HPLC) >= 95% Solubility DMSO

and Hoechst Janelia Fluor 646 (Hoechst-JF646)

DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE deuterium-labeled-aldehyde 664 SMILES NCCOCCOCCOCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate

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