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Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8) Size:100mg Product Name [4-(methoxy-d3)phenyl]methanol Synonyms [4-(²H3)methoxyphenyl]methanol

SKU 62690211583
4.2
EUR245.00 EUR269.00

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Description

Product Name [4-(methoxy-d3)phenyl]methanol Synonyms [4-(²H3)methoxyphenyl]methanol CAS Number 14629-71-1 Related CAS Molecular Formula C8H10O2 Molecular Weight 141

SuO-Glu-Val-Cit-PAB-MMAE (NHS-Glutarate-Val-Cit-PAB-MMAE) is a cleavable ADC linker–payload system consisting of a SuO-Glu-Val-Cit-PAB peptide linker and the microtubule-disrupting cytotoxic payload MMAE

SiR-NHS is the NHS ester of SiR-6-COOH (652Ex/674Em) and can be conjugated to amine-containing molecules easily

Product Name DKY709 Synonyms CAS Number 2291360-73-9 Related CAS Molecular Formula C25H27N3O3 Molecular Weight 417

042 SMILES [2H]C([2H])([2H])OC1=NC=C(Br)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8) Size:100mg Product Name [4-(methoxy-d3)phenyl]methanol Synonyms [4-(²H3)methoxyphenyl]methanolSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility.

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