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both blocking kinase signaling and inducing down-regulation of the mutant p110alpha protein level in a dose-dependent and time-dependent manner
Product Name: DBCO NHS Synonyms: CAS Number: 1353016-71-3 Molecular Formula: C23H18N2O5 Molecular Weight: 402
Product Name 3-(methoxy-d3)aniline Synonyms 3-(²H3)methoxyaniline CAS Number 1820607-08-6 Related CAS Molecular Formula C7H9NO Molecular Weight 126
Product Name DOTA-butyne Synonyms CAS Number 2125661-62-1 Related CAS Molecular Formula C20H33N5O7 Molecular Weight 455
S)-AHPC-CO-C3-NH2 HCl Synonyms CAS Number 2940858-65-9 Related CAS 2361119-88-0 (free base)
DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Size:5mg both blocking kinase signaling andSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further
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