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Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE payload Product Name Thalidomide-O-C3-acid Synonyms Thalidomide-4'-O-C3-acid

SKU 59698360055
4.9
USD495.00 USD518.00

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Description

Product Name Thalidomide-O-C3-acid Synonyms Thalidomide-4'-O-C3-acid CAS Number 2169266-64-0 Related CAS Molecular Formula C17H16N2O7 Molecular Weight 360

Product Name CP-SS-SulfoCy5 Synonyms SNAP2-SS-SulfoCynine 5 CAS Number Related CAS Molecular Formula C50H60ClN7O8S4 Molecular Weight 1050

where they serve as highly potent cytotoxic payloads

1038/s41589-020-0594-x

SHP099 is a highly potent (IC50 = 0

Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE payload Product Name Thalidomide-O-C3-acid Synonyms Thalidomide-4'-O-C3-acidSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Azide Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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