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Product Name DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C63H91N9O17 Molecular Weight 1246
This modification makes it non-fluorescent in its initial state (a "pro-fluorophore")
Product Name Lenalidomide-CO-C3-acid Synonyms Lenalidomide-4'-CO-C3-acid CAS Number 1334496-37-5 Related CAS Molecular Formula C18H19N3O6 Molecular Weight 373
403 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(NCCOCCOCC#C)=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
The succinyl group mimics a biologically relevant post-translational modification (lysine succinylation)
DBCO-Dap(m-PEG4)-Val-Ala-PAB dbco-dap-m-PEG4 Product Name DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4) Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,
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