Fmoc-Val-Cit-PAB(m-PEG4)-PNP map555 384 SMILES OCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC)

384 SMILES OCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

576 Purity (HPLC) >= 95% Solubility DMSO

387 SMILES OCCOCCOCC#CC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Biochemistry

493 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)ON2C(=O)CCC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Fmoc-Val-Cit-PAB(m-PEG4)-PNP map555 384 SMILES OCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned