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48 SMILES Cl
Protein degradation technology: a strategic paradigm shift in drug discovery
Product Name DOTA-PEG3-C2-amine Synonyms CAS Number 2866181-79-3 Related CAS Molecular Formula C24H46N6O10 Molecular Weight 578
Product Name Lenalidomide-PEG5-C2-acid Synonyms Lenalidomide-4'-PEG5-C2-acid CAS Number 2376139-68-1 Related CAS Molecular Formula C26H37N3O10 Molecular Weight 551
118 Purity (HPLC) >= 95% Solubility DMSO
DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4) Size:50mg 48 SMILES ClSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further
