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DCAF1 Binder 13 is a potent and selective DCAF1 binder
both blocking kinase signaling and inducing down-regulation of the mutant p110alpha protein level in a dose-dependent and time-dependent manner
Product Name Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C78H108FN9O25 Molecular Weight 1590
227 Purity (HPLC) >= 95% Solubility DMSO
Product Name Thalidomide-5'-C7-OH Synonyms CAS Number 2493430-96-7 Related CAS Molecular Formula C20H24N2O5 Molecular Weight 372
MC-Gly-Gly-Phe-Gly-PAB(m-PEG8) Size:25mg DCAF1 Binder 13 is aSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be
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