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Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8) ggfg N-di(methyl-d3)aniline Synonyms 3-bromo-N

SKU 48102661822
4.5
USD195.00 USD240.00

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Description

N-di(methyl-d3)aniline Synonyms 3-bromo-N

625 Purity (HPLC) >= 95% Solubility DMSO

Chloropyrimidine (CP) derivatives generally exhibit better cell permeability compared to their benzylguanine (BG) derivatives

336 Purity (HPLC) >= 95% Solubility DMSO

722 SMILES: [O-]C(=O)C1=CC=C(C=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCCCN=[N]#N

Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8) ggfg N-di(methyl-d3)aniline Synonyms 3-bromo-NSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker

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