TMX-4100 Size:10mg 5 SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCN=[N+]=[N-])[C@@]1([H])NC(=O)N2 Purity (HPLC)

5 SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCN=[N+]=[N-])[C@@]1([H])NC(=O)N2 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

391 SMILES OCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

972 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCCOCCO)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-5'-propargyl-amine HCl Synonyms CAS Number 2490402-61-2 Related CAS Molecular Formula C16H14ClN3O4 Molecular Weight 347

TMX-4100 Size:10mg 5 SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCN=[N+]=[N-])[C@@]1([H])NC(=O)N2 Purity (HPLC)TMX 4100 is a selective phosphodiesterase 6D (PDE6D) degrader. TMX 4100 shows a high degradation preference for PDE6D with the DC50 values less than 200 nM in MOLT4, Jurkat, and MM. 1S cells. TMX 4100 can be used for the research of multiple myeloma. Product Name TMX 4100 Synonyms CAS Number 2367619 63 2 Related CAS Molecular Formula C11H10N4O2S Molecular Weight 262. 29 SMILES O=C1CCC(N2C=C(N=N2)C2=CSC=C2)C(=O)N1 Purity (HPLC) >= 95% Physical