Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG4) tamra Product Name Pomalidomide-PEG2-C2-acid Synonyms Pomalidomide-4'-PEG2-C2-acid

Product Name Pomalidomide-PEG2-C2-acid Synonyms Pomalidomide-4'-PEG2-C2-acid CAS Number 2140807-17-4 Related CAS Molecular Formula C20H23N3O8 Molecular Weight 433

Product Name DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C97H119FN12O27 Molecular Weight 1904

Product Name DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C110H170N14O30 Molecular Weight 2168

Product Name: 5(6)-TMARA C2 maleimide Synonyms: Tetramethylrhodamine-5(and 6) C2 maleimide CAS Number: N/A Molecular Formula: C31H28N4O6 Molecular Weight: 552

making the linkers highly adaptable for diverse ADC and related applications

Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG4) tamra Product Name Pomalidomide-PEG2-C2-acid Synonyms Pomalidomide-4'-PEG2-C2-acidSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX