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It is based on a proximity-induced covalent Michael addition between an engineered cysteine (Cys) residue in Escherichia coli dihydrofolate reductase (eDHFR) and optimized trimethoprim (TMP)-acrylamide conjugates with minimal linker lengths
221 SMILES [2H]C([2H])([2H])OC1=CC=C(CC(=O)OC)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Product Name: Coumarin hydrazine Synonyms: Coumarin hydrazine CAS Number: N/A Molecular Formula: C10H10N2O2 Molecular Weight: 190
Product Name: 5(6)-ROX Synonyms: 5-(and 6)-Carboxy-X-rhodamine CAS Number: 198978-94-5 Molecular Formula: C33H30N2O5 Molecular Weight: 534
507 SMILES [H][C@@]1(CCC(=O)NC1=O)N1CC2=C(C=CC=C2OCC2=CC=C(CN3CCOCC3)C=C2)C1=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO
DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:100mg It is based on aSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further
