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Product Name Thalidomide-C3-PEG4-C2-Br Synonyms Thalidomide-4'-C3-PEG4-C2-Br CAS Number n/a Related CAS Molecular Formula C26H35BrN2O9 Molecular Weight 599
92 SMILES Cl
highlighting its strong affinity and potential as a precision tool in targeted protein degradation studies
Product Name 3-Bromo-4-(methoxy-d3)-5-methoxybenzaldehyde Synonyms CAS Number n/a Related CAS Molecular Formula C9H9BrO3 Molecular Weight 248
inhibitor screening
Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8) peg3 Product Name Thalidomide-C3-PEG4-C2-Br Synonyms Thalidomide-4'-C3-PEG4-C2-BrSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX
