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Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG8)-MMAE bronic ester CA-Vbn (Vinylbenzoyl-Halo) is a HaloTag

SKU 40898705757
4.1
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Description

CA-Vbn (Vinylbenzoyl-Halo) is a HaloTag ligand containing an alkene group

585 Purity (HPLC) >= 95% Solubility DMSO

SPAAC is copper-free

https://clinicaltrials

TMP3-TMR is a third-generation covalent TMP-tag designed for improved efficiency in protein labeling and interaction studies

Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG8)-MMAE bronic ester CA-Vbn (Vinylbenzoyl-Halo) is a HaloTagSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly

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