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17515–17523
Product Name: Texas Red lysine Synonyms: Sulforhodamine 101 lysine CAS Number: N/A Molecular Formula: C37H42N4O8S2 Molecular Weight: 734
Product Name MC-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C90H138N12O25 Molecular Weight 1788
Product Name Thalidomide-O-acetamido-PEG4-C2-azide Synonyms Thalidomide-4'-O-acetamido-PEG4-C2-azide CAS Number 2411681-89-3 Related CAS Molecular Formula C25H32N6O10 Molecular Weight 576
amine-containing groups
Mal-Acetyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-MMAE Size:5mg 17515–17523SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate
