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Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP dbco-propionyl The BODIPY FL thalidomide-mediated Cereblon

SKU 38648032797
4.4
USD445.00 USD485.00

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Description

The BODIPY FL thalidomide-mediated Cereblon Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay

SulfoCy3(Sulfo-Cyanine3

456 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(NCCOCCOCCOCC#C)C=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

097 SMILES [2H]C([2H])([2H])NCC1=CC=C(Br)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

94 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCOCCN=[N+]=[N-])C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP dbco-propionyl The BODIPY FL thalidomide-mediated CereblonSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase

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