Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Product Name Phthalimidinoglutarimide-propargyl-O-PEG1-C2-amine HCl Synonyms

Product Name Phthalimidinoglutarimide-propargyl-O-PEG1-C2-amine HCl Synonyms Phthalimidinoglutarimide-4'-propargyl-O-PEG1-C2-amine HCl CAS Number 2138440-68-1 Related CAS Molecular Formula C20H24ClN3O5 Molecular Weight 421

Product Name Pomalidomide-5'-C4-azide Synonyms CAS Number n/a Related CAS Molecular Formula C17H18N6O4 Molecular Weight 370

Product Name Thalidomide-5'-piperazine-C2-piperazine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C23H33Cl3N6O4 Molecular Weight 563

Product Name Thalidomide-O-PEG2-OH Synonyms Thalidomide-4'-O-PEG2-OH CAS Number 2581818-54-2 Related CAS Molecular Formula C17H18N2O7 Molecular Weight 362

Product Name CA-Oregon Green Synonyms Oregon Green-Halo

Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Product Name Phthalimidinoglutarimide-propargyl-O-PEG1-C2-amine HCl SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,