SHP099 deuterium-labeled-carboxylic acid 23 SMILES CC1=CC=C(C=C1)S(=O)(=O)N\N=C\C1=C(O)C=CC(Br)=C1 Purity (HPLC)

23 SMILES CC1=CC=C(C=C1)S(=O)(=O)N\N=C\C1=C(O)C=CC(Br)=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Product Name Pomalidomide-CO-PEG1-C2-Cl Synonyms Pomalidomide-4'-CO-PEG1-C2-Cl CAS Number n/a Related CAS Molecular Formula C18H18ClN3O6 Molecular Weight 407

Product Name CA-DOTA-tris(t-Bu) Synonyms HaloTag DOTA-tris(t-Bu) Ligand

Contains an E3 ligase ligand with PEG linker and terminal alcohol

Product Name DOTA-tris(t-Bu)ester-PEG5-C2-propanamido-maleimide Synonyms CAS Number n/a Related CAS Molecular Formula C47H83N7O15 Molecular Weight 986

SHP099 deuterium-labeled-carboxylic acid 23 SMILES CC1=CC=C(C=C1)S(=O)(=O)N\N=C\C1=C(O)C=CC(Br)=C1 Purity (HPLC)SHP099 is a highly potent (IC50 = 0. 071uM),selective and orally bioavailable small molecule SHP2 inhibitor. The inhibiting SHP2 activity of SHP099 is through an allosteric mechanism. SHP099 suppresses RASERK signalling to inhibit the proliferation of receptor tyrosine kinase driven human cancer cells in vitro and is efficacious in mouse tumour xenograft models. Product Name SHP099 Synonyms CAS Number 1801747 42 1 Related CAS Molecular Formula