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DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE adc Product Name Pomalidomide-CO-C2-acid Synonyms Pomalidomide-4'-CO-C2-acid

SKU 29191221179
4.8
EUR495.00 EUR521.00

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Description

Product Name Pomalidomide-CO-C2-acid Synonyms Pomalidomide-4'-CO-C2-acid CAS Number 2417174-32-2 Related CAS Molecular Formula C17H15N3O7 Molecular Weight 373

601 Purity (HPLC) >= 95% Physical Appearance Orange Solid Optical Properties Abs/Em Maxima: 494/526 nm Solubility DMSO

684 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2C([O-])=O)C(=O)NCCOCCOCCOCC#C)=[N+](C)C)=C1

Product Name Thalidomide-O-C3-Br Synonyms Thalidomide-4'-O-C3-Br CAS Number n/a Related CAS Molecular Formula C16H15BrN2O5 Molecular Weight 395

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DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE adc Product Name Pomalidomide-CO-C2-acid Synonyms Pomalidomide-4'-CO-C2-acidSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to

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