Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG8)-MMAE Size:10mg 591 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC)

591 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name TMP-POM 7c Synonyms TMP-Pomalidomide 7c CAS Number Related CAS Molecular Formula C36H44N8O10 Molecular Weight 748

Product Name tert-butyl 2-{4-[(piperidin-4-yl)methyl]piperazin-1-yl}acetate Synonyms CAS Number n/a Related CAS Molecular Formula C16H31N3O2 Molecular Weight 297

Product Name Thalidomide-O-acetamido-C4-azide Synonyms Thalidomide-4'-O-acetamido-C4-azide CAS Number 2098488-36-7 Related CAS Molecular Formula C19H20N6O6 Molecular Weight 428

Product Name Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C88H146N10O26 Molecular Weight 1760

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG8)-MMAE Size:10mg 591 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly