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324 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(NCCC#C)=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
5(6)-FAM PEG3 azide is an excellent alkyne-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemistry
CA-Oregon Green is a cell permeable HaloTag fluorescent ligand and can be used to label intracellular proteins (496Ex/516Em after hydrolysis)
066 Purity (HPLC) >= 95% Solubility DMSO
Sulforhodamine 101 emits at a longer wavelength than does either Tetramethylrhodamine or Sulforhodamine B
DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan payload 324 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(NCCC#C)=CC=C12 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
