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Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan dmea CC(C)(C)C(=O)OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCOCCOCCOCC#C)C1=CC=C(OC(=O)C(C)(C)C)C=C1O2 Purity (HPLC): ≥ 95%

SKU 18200679086
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Description

CC(C)(C)C(=O)OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCOCCOCCOCC#C)C1=CC=C(OC(=O)C(C)(C)C)C=C1O2 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

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SNAP-tag reacts with covalently with O6-benzylguanine (BG) derivatives

727 Purity (HPLC) >= 95% Solubility DMSO

Product Name Lenalidomide-CO-C3-OH Synonyms Lenalidomide-4'-CO-C3-OH CAS Number n/a Related CAS Molecular Formula C17H19N3O5 Molecular Weight 345

Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan dmea CC(C)(C)C(=O)OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCOCCOCCOCC#C)C1=CC=C(OC(=O)C(C)(C)C)C=C1O2 Purity (HPLC): ≥ 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent

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