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Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8)-Exatecan Size:10mg Identification of Potent

SKU 18158668121
4.6
EUR445.00 EUR466.00

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Description

Identification of Potent

S)-AHPC-CO-PEG1-C2-Cl Synonyms CAS Number n/a Related CAS Molecular Formula C27H37ClN4O5S Molecular Weight 565

SNAP2-Cp CAS Number Related CAS Molecular Formula C18H19ClN4O3 Molecular Weight 374

S)-AHPC-CO-C4-piperazine HCl Synonyms CAS Number 2446803-40-1 Related CAS Molecular Formula C31H48Cl2N6O4S Molecular Weight 671

MaP555-Alkyne is is a fluorogenic probe

Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8)-Exatecan Size:10mg Identification of PotentSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I

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