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HaXS8 cy3 Nature Chemical Biology

SKU 14084971330
4.5
USD195.00 USD218.00

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Description

Nature Chemical Biology

Product Name Thalidomide-O-PEG4-C2-amine HCl Synonyms Thalidomide-4'-O-PEG4-C2-amine HCl CAS Number 2820929-03-9 Related CAS 2401832-00-4 (free base) Molecular Formula C23H32ClN3O9 Molecular Weight 529

Product Name Pomalidomide-PEG5-C2-azide Synonyms Pomalidomide-4'-PEG5-C2-azide CAS Number 2624181-61-7 Related CAS Molecular Formula C25H34N6O9 Molecular Weight 562

Datasheet         MSDS        COA

Product Name Lenalidomide-CO-C6-Br Synonyms Lenalidomide-4'-CO-C6-Br CAS Number n/a Related CAS Molecular Formula C20H24BrN3O4 Molecular Weight 450

HaXS8 cy3 Nature Chemical BiologyHaXS8 is a synthetic chemical dimerizer designed to induce covalent and irreversible intracellular dimerization between proteins tagged with HaloTag and SNAP tag. Its a bifunctional molecule featuring a chloroalkane group (specific for HaloTag) and an O6 benzylguanine (BG) derivative (specific for SNAP tag), connected by a flexible polyethylene glycol (PEG) linker. When introduced to cells, HaXS8 bridges HaloTag and SNAP tag fusion proteins by

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