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Oregon Green resists fading under prolonged illumination better than fluorescein
Product Name Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C71H94FN11O22 Molecular Weight 1472
emission maximum = 660 nm
S)-AHPC-acetamido-O-C2-Cl Synonyms CAS Number n/a Related CAS Molecular Formula C26H35ClN4O5S Molecular Weight 551
Product Name NDB-TM Synonyms CAS Number 871510-38-2 Related CAS Molecular Formula C10H10N4O3S Molecular Weight 266
Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-Exatecan tmr Oregon Green resists fading underSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I
